This book uses a case presentation style and a question-and-answer format to focus on commonly encountered surgical pathology in the fields of general surgery, urology, and otolaryngology. This is an update of the 2010 edition incorporates new cancer staging guidelines (AJCC Cancer Staging Manual, 7th edition, Edge et al. (Springer, 2010)) and fixes errors. Purpose The purpose is to use clinical cases followed by relevant questions with answers to present the pathophysiology of the disease, appropriate workup with a focus on clinical history and exam findings, and treatment. It strives to concisely present the relevant information to allow students to assimilate the appropriate approach to clinical conditions, and in most cases, it succeeds. Audience It is appropriately aimed at medical students and junior level residents. It is in no way comprehensive for any of the fields it addresses (general surgery, otolaryngology, or urology), but rather an interesting group of cases which can supplement the readers’ base knowledge. Features The book presents cases both by diagnosis (for example, breast cancer, head and neck cancer, skin cancer, and hernias) and by physical exam finding (jaundice, unilateral lower extremity swelling). These cases are reminiscent of rounds with an attending, working through a disease process using a patient’s case presentation as a starting point. There are useful photographs and diagrams presenting physical exam findings, with many of the photographs depicting very obvious and advanced clinical signs of the disease. It would be helpful to organize the book into cases presented as an exam finding and then cases presented as a diagnosis. It seems to be loosely organized in a head-to-toe fashion, but at times feels as if it skips around with little reason. Assessment This book offers a unique case presentation format with easily readable and digestible information. It would be a valuable adjunct to textbook reading for upper level medical students and intern level residents, allowing them to cement the important information from the chapters. Some of the information is irrelevant for U.S. students, as it quotes incidence of disease in India. There are also some minor discrepancies in treatment (for example sentinel lymph node biopsy in patients without known axillary involvement rather that standard axillary lymph node dissection in breast cancer).